Support and Funding

The center has enjoyed great success from its intense research focus and innovation by having been awarded in excess of $25 million in research funding from the most competitive funding sources such as the National Institutes of Health (NIH), the American Diabetes Association (ADA), and the American Heart Association (AHA). In the last few years, the center’s science output has been very prolific resulting in an average of ten research papers a year published in the most preeminent scientific journals in the United States and internationally. These include high impact publications such as Nature Medicine, Journal of Clinical Investigation, Circulation, Circulation Research, to name a few.

  • Autophagy VSMC migration
  • Oxidant stress and diabetic endothelial dysfunction
  • Angiotensin-II, GTPCH1 and 26S proteasome
  • Reactive nitrogen species and accelerated atherosclerosis in Type I diabetes
  • Control VSMC Proliferation and Migration
  • AMP-activated kinase in diabetic complications
  • AMPK as a redox sensor and modulator
  • Sirt1, Vascular Aging, and Aortic Aneurysm
  • Defective autophagy-dependent mitochondrial clearance and diabetic cardiomyopathy
  • Macrophage Liver Kinase B1 in atherosclerosis, Postdoctoral Fellowship awarded to Dr. Zhaoyu Liu
  • The role of FUNDC1 in Mitochondrial Dynamics in Cardiomyocytes, Postdoctoral Fellowship awarded to Dr. Shengnan Wu
  • The role of AMPKalpha2 in vascular smooth muscle cell phenotypic switching and atherosclerotic plaque instability, Postdoctoral Fellowship awarded to Dr. Ye Ding
  • Autophagy suppression and mitochondrial fission in endothelial cells, Grant-in-Aid awarded to Dr. Zhonglin Xie
  • Liver kinase B1 and autophagy regulation in Vascular smooth muscle cells, a three-year NIH Minority Faculty Award to Dr. Imoh Okon
  • NIH grant to study “Liver kinase B1 and tumor angiogenesis”