Support and Funding

The center has enjoyed great success from its intense research focus and innovation by having been awarded in excess of $35 million in research funding from the most competitive funding sources such as the National Institutes of Health (NIH), the American Diabetes Association (ADA), and the American Heart Association (AHA). In the last few years, the center’s science output has been very prolific resulting in an average of ten research papers a year published in the most preeminent scientific journals in the United States and internationally. These include high impact publications such as Nature Medicine, Journal of Clinical Investigation, Circulation, Circulation Research, to name a few.

The center has enjoyed great success from its intense research focus and innovation by having been awarded in excess of $25 million in research funding from the most competitive funding sources such as the National Institutes of Health (NIH), the American Diabetes Association (ADA), and the American Heart Association (AHA). In the last few years, the center’s science output has been very prolific resulting in an average of ten research papers a year published in the most preeminent scientific journals in the United States and internationally. These include high impact publications such as Nature Medicine, Journal of Clinical Investigation, Circulation, Circulation Research, to name a few.

 


 

  • AMP-activated Protein Kinase in Diabetes, awarded to Dr. Ming-hui Zou
  • AMP-activated kinase in diabetic complications -Completed
  • AMPK as a redox sensor and modulator -Completed
  • The role of AMPKalpha2 in vascular smooth muscle cell phenotypic switching and atherosclerotic plaque instability, Postdoctoral Fellowship awarded to Dr. Ye Ding -Completed
  • Angiotensin-II, GTPCH1 and 26S proteasome -Completed
  • Autophagy and diabetic vascular diseases -Completed
  • Suppression of Autophagy-Dependent Clearance Mitochondria in Type 2 Diabetes, awarded to Dr. Zhonglin Xie and Dr. Ming-hui Zou
  • Autophagy suppression and mitochondrial fission in endothelial cells, Grant-in-Aid awarded to Dr. Zhonglin Xie -Completed
  • Autophagy and Diabetic Vascular Diseases, awarded to Dr. Ming-hui Zou
  • Autophagy and VSMC migration; awarded to Dr. Zhonglin Xie and Dr. Ming-hui Zou
  • Control VSMC proliferation and migration -Completed
  • Chemokine Signaling in EPC Angiogenesis: A Role of Lysine Methylation, awarded to Dr. Chunying Li
  • Controlling Atherosclerotic Plaque Stability, awarded to Dr. Ming-hui Zou
  • Defective autophagy-dependent mitochondrial clearance and diabetic cardiomyopathy -Completed
  • Elucidating Novel Roles of Mitochondria FUNDC1 Receptor in Obesity-Instigated Angiogenesis, Career Development Award awarded to Dr. Imoh Okon
  • FUNDC1 and Diabetic Cardiomyopathy, awarded to Dr. Zhonglin Xie and Dr. Ming-hui Zou
  • The role of FUNDC1 in mitochondrial dynamics in cardiomyocytes, Postdoctoral Fellowship awarded to Dr. Shengnan Wu -Completed
  • Inflammasome and Unstable Atherosclerotic Plaques, awarded to Dr. Ming-hui Zou
  • Inflammasome in Smoking-Promoted Atherosclerotic Plaque Rupture, Career Development Award awarded to Dr. Ye Ding
  • Intrinsic Stiffness of Aortic Vascular Smooth Muscle Cell in the Development of Hypertension, awarded to Dr. Hongyu Qiu
  • Ketogenic-Diet Potently Inhibits Abdominal Aortic Aneurism Formation, Postdoctoral Fellowship awarded to Dr. Young-min Han
  • Kynureninase Inhibition Ablates AngII-Induced 3-HJydroxyanthranilic Acid Mediated Abdominal Aortic Aneurysm Formation, Postdoctoral Fellowship, awarded to Dr. Ramprasath Tharmarajan
  • Liver kinase B1 and autophagy regulation in Vascular smooth muscle cells, a three-year NIH Minority Faculty Award to Dr. Imoh Okon -Completed
  • Liver Kinase B1 in Angiogenesis, awarded to Dr. Ming-hui Zou
  • Macrophage liver kinase B1 in atherosclerosis, Postdoctoral Fellowship awarded to Dr. Zhaoyu Liu -Completed
  • The Role of the Mitochondria and Endoplasmic Reticulum Contacts in Diabetic Cardiomyopathy, Career Development Award awarded to Dr. Shengnan Wu
  • MKP1, VSMC, and Vascular Remodeling, awarded to Dr. Ping Song and Dr. Ming-hui Zou
  • Novel Mechanism Mediating Cardiac Protection Upon Pressure Overload, awarded to Dr. Hongyu Qiu
  • Oxidant stress and diabetic endothelial dysfunction -Completed
  • Reactive nitrogen species and accelerated atherosclerosis in Type I Diabetes -Completed
  • SNRK in Ischemic Vascular Diseases, awarded to Dr. Zhonglin Xie and Dr. Ming-hui Zou
  • SIRT1, vascular aging, and aortic aneurysm, awarded to Dr. Ming-hui Zou
  • Role of VCP in Coronary Ischemic Injury, awarded to Dr. Hongyu Qiu